1876 May 29 John Cunningham's Feed Store on West Main St., damaged or destroyed 13 buildings
1894 Aug. 12 Braddock block, corner of Main and Church St.
1902 July 4 Zimmerman building on Main St.
1906 Nov. 24 Lemmon's Livery Stable on the Diamond
1915 Jan. 3 Visitation Church on Walnut St., destroyed and an adjacent school gutted
1915 Jan 22 St. Joseph's Church on South Shupe and Summit St.
1915 Nov. 29 Kobacker's store on Main St.
1930 Nov. 4 Santoro building on East Main St.
1942 Dec. 8 Montgomery Ward, Burns Drug and Angeles Restaurant
1947 Nov. 19 Antonette building Diamond and Washington St., 5 fatalities, the single largest lose of life in a fire in Mt. Pleasant.
1967 Jan. 12 Moose on East Main St.
1967 March 14 East End Restaurant, Main St. between Cherry and Shupe
1970 Nov. 29 Journal Office and Knight's of Columbus
1977 Feb. 23 Landy's Garage, East Main St.
1977 Feb. 27 Burns Drug and Peoples Wallpaper and Paint, West Main St.
1979 Aug. 18 Mt. Pleasant Auto Parts West Main St.
1979 Nov. 21 Harmon Mansion, South Church St.
1981 Oct. 18 National Hotel, West Main St.
1981 Nov. 13 Presbyterian Church, West Main St.
1986 May 3 Map Hotel, West Main St.
1986 Oct. 24 Rega Tailor Shop, West Main St.
1989 Dec. 15 Northwind Construction
1991 August Cernuto building on West Main St., 3 fatalities
1995 Sept. 6 George and Cunningham Hardware on West Main St.
1996 March 16 Harmon House Nursing Home, South Church St., 1 fatality
1998 Aug. 8 Levin Warehouse, possibly the biggest fire ever to occur in Mt. Pleasant in regards to the size of the structure and the amount of equipment and manpower required to fight it.